Andrew Gao's research efforts

Google Scholar profile:

scholar.google.com

Bovine Leukemia Virus

As an intern at the UCSD Supercomputer Center, I researched bovine leukemia virus and how it may lead to breast cancer in humans.

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Check out my paper on how a common cow disease might lead to breast cancer in humans!

Bovine leukemia virus relation to human breast cancer: Meta-analysis

Bovine leukemia virus (BLV) is a virus that infects cattle around the world and is very similar to the human T-cell leukemia virus (HTLV), which causes adult T-cell leukemia/lymphoma (ATL). Recently, presence of BLV DNA and protein was demonstrated in ...

www.ncbi.nlm.nih.gov

Bovine leukemia virus relation to human breast cancer: Meta-analysis

Lung Cancer Detection

I conducted experiments on DNA methylation signatures of plasma samples from lung cancer patients. The application would be for a non-invasive diagnostic test.

Full Abstract

Category: Translational Medical Science Finalist Names: Gao, Andrew (School: Canyon Crest Academy) Abstract: The American Cancer Society projects that over 135,000 Americans will die from lung cancer in 2020. It is recognized that the earlier lung cancer is detected, the higher the survival rate and the lower the treatment cost.

abstracts.societyforscience.org

I also performed bioinformatics analyses on microRNA expression profiles in lung cancer serum samples.

Integrative Bioinformatics Analysis Identifies Noninvasive miRNA Biomarkers for Lung Cancer

Non-small cell lung cancer (NSCLC), a subtype of lung cancer, affects millions of people. While chemotherapy and other treatments have improved, the 5 year survival rate of NSCLC patients is still only 21%. Early diagnosis is essential for increasing survival as treatments have higher effectiveness at earlier stages of NSCLC.

www.medrxiv.org

Blood-based Diagnostic Biomarkers for Parkinson's

I identified several promising biomarkers for detecting Parkinson's disease from blood samples. I received a total of $28,000 in scholarships for my work.

Identification of Blood-based Biomarkers for Early Stage Parkinson's Disease

Parkinson's disease (PD) affects millions of people worldwide and causes symptoms such as bradykinesia and disrupted speech. Parkinson's disease is known to be characterized by the mass death of dopaminergic neurons in the substantia nigra region. In the status quo, PD is often diagnosed at late stages because obvious motor symptoms appear after the disease has progressed far.